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Evaluation of antidiabetic potential of the hydroalcoholic extract of Withania coagulans Dunal dried fruit (WCDF) alone and in combination with Glipizide, in streptozotocin-induced diabetes, and evaluation of possible antihyperlipidemic activity of the same extract in high-cholesterol diet-induced hyperlipidemia, in albino rats.

Other names for this medication:
Glipizide, Actine, Dipazide, Gabaz, Glibenese, Glide, Glidiab, Glipizida, Glucotrol, Glynase, Melizide, Mindiab, Minodiab, Ozidia, Sucrazide,

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Glipizide is used to treat high blood sugar levels caused by a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. In type 2 diabetes, your body does not work properly to store excess sugar and the sugar remains in your bloodstream. Chronic high blood sugar can lead to serious health problems in the future.

Proper diet is the first step in managing type 2 diabetes, but often medicines are needed to help your body. Glipizide belongs to a class of drugs called sulfonylureas. It stimulates the release of insulin from the pancreas, directing your body to store blood sugar. This helps lower blood sugar and restore the way you use food to make energy.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet, Extended Release
  • Tablet

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Combination of controlled differentiation with ground-breaking technologies for the reversal of somatic cells to an ES cell-like state promise the generation of patient-derived pluripotent cell lines for the treatment of disease in the future. Suppression of hepatitis B virus-derived human hepatocellular carcinoma by NF-kappaB-inducing kinase-specific siRNA using liver-targeting liposomes.

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Different plate designs containing identical probe material were formulated to accommodate different robotic and pin designs. Using three sets of PBDE elimination half-lives, we applied a population pharmacokinetic model to the PBDE biomonitoring data measured between 2002-2003 and 2010-2011 to derive the top-down uptake rates of four key PBDE congeners and six age groups.

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To determine the value of pattern visual evoked potential (PVEP) testing with 5 consecutive check-size patterns in presumably malingering draftees. Our findings suggest that bisphosphonates may be useful in controlling disease progression in GCTB and that these agents directly inhibit GCTB - derived osteoclast resorption. In conclusion, RT-PCR is more sensitive and rapid than are standard microbiological methods for the detection of bacterial pathogens on food contact surfaces. The fractionation ranged between 0.52 per thousand and 27 per thousand, with largest fractionations were found at intermediate temperatures and the smallest fractionations at the lowest and highest temperatures.

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The cardiovascular consequences of the metabolic syndrome and its component risk factors have been documented in elderly individuals. The samples were collected from patients suspected of having pulmonary tuberculosis, were examined using a PCR amplified IS6110 insertion element in comparison to Ziehl-Neelsen stained smears in terms of sensitivity and specificity. The main limitations are the use of a post hoc analysis and the pooling of two studies with slightly different designs.

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Further use was made of questionnaires concerning bio-demographic data, work assessment, and the characteristics of the bowling game. Surgical treatment place in the management of prostate cancer: report of 96 cases In Drosophila females, germline stem cells (GSCs) require Sex lethal (Sxl) to exit the stem cell state and to enter the differentiation pathway. DSCG strongly inhibited IL-4-dependent IgE production by lipopolysaccharide-stimulated murine whole spleen cells.

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On-chip chemiluminescent signal enhancement using nanostructured gold-modified carbon microarrays. In the 6th treatment cycle, the serum NET levels were either 0.5 ng/ml or below.

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cockerelli, a species with derived social organization, workers produce fertility signals identical to the queen. This formulation permits the thermal performance of fiber-optic strain gauges to be compared with conventional resistive gauges. mutans was overexpressed in Escherichia coli strain BL21 (DE3), purified to homogeneity and crystallized using the hanging-drop vapour-diffusion method.

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Dravet syndrome (severe myoclonic epilepsy in infancy): a retrospective study of 16 patients. Among GERD patients, male gender, high body mass index, high obesity degree, high waist-to-hip ratio, high triglycerides, alcohol intake, smoking and the presence of a hiatal hernia were positively related to the development of erosive esophagitis compared to NERD. By quantitative (q)RT-PCR, expression of MMP-13 was significantly increased in RBM tissues relative to that in RCC and adjacent normal kidney while no differences in the expression of MMP-1, -2, -8, or -9 mRNA were observed. The primary locus of motor neuron death in an ALS-PDC mouse model. The relative contribution of each cell type to the response was found to vary considerably and could be use to define the interexperimental variation.

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Male CD47 deficient and wild type (WT) control mice were fed with either low fat (LF) or high fat (HF) diets for 16 weeks. Interim treatment selection using the normal approximation approach in clinical trials.

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Optimal pressure regulation of the pneumatic ventricular assist device with bellows-type driver. The abundance and activity of three subgroups of mitogen-activated protein (MAP) kinases, the extracellular signal regulated kinase 1 (ERK1), stress-activated protein kinase 1/ Jun N-terminal kinase (SAPK1), and stress-activated protein kinase 2/ p38 (SAPK2), were measured in gill epithelium of the euryhaline teleost Fundulus heteroclitus exposed for 1 h to 4 weeks to hyper- and hyposmotic stress. Herpes simplex virus type 1 (HSV-1) requires four glycoproteins to complete membrane fusion, but none has been defined as class I or II.

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Mycolyltransferase from Mycobacterium leprae excludes mycolate-containing glycolipid substrates. The intermediates show typical molten globule characteristics (secondary structure content similar to the native and less tight packing of the side chains), in agreement with the belief that partly folded states play a key role in protein aggregation.

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Our findings support the hypothesis that new and emerging infectious agents, or new forms of immune-mediated encephalitis, may be responsible for cases currently of unknown cause and encourage the ongoing global effort to identify these. Structural features of arabinogalactan-proteins from the fruit of Lycium chinense Mill.

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We have introduced intensive virologic surveillance for adenovirus in our institution including at least weekly polymerase chain reaction testing of blood and stool samples. The FDP tendon was re-attached to the distal phalanx using the pull-out technique with a non-absorbable polyethylene suture. Synthesis of 3-substituted 2-fluoro- and 2,2-difluoroaziridines. MEF nanoballs consist of a approximately 130 nm silver nanoparticle core, a silica shell with up to 35 nm thickness and fluorophores doped within the silica shell.

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However, non-coding functional elements can also be located within coding region, as is common for exonic splicing enhancers, some transcription factor binding sites, and RNA secondary structure elements affecting mRNA stability, localization, or translation. Survival and death of mature avian motoneurons in organotypic slice culture: trophic requirements for survival and different types of degeneration.

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Double-blind randomised controlled trial, 2:1 randomisation NovaSure versus ThermaChoice. They are up to three times more resistant to UVA radiation and two times more resistant towards hydrogen peroxide treatment.

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We have reported two kinds of viruslike particles derived from human sera that induced morphologically and serologically different types of non-A, non-B hepatitis in chimpanzees. Additionally, FSH may be involved in the maintenance of cholesterol side chain cleavage activity, the C17-C20 lyase and the 17 beta hydroxysteroid dehydrogenase in the adult rat.

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Apparently, potential bottlenecks in phenylalanine seem to hardly change in the course of a batch fermentation. We report a case of spondylocostal dysosotosis in a patient born to consanguineous turkish parents, and review the clinical and genetic data on that group of skeletal disorders. Furthermore, the conflict-sensitive N2 components of the event-related brain potential were similar in amplitude, but showed significantly different scalp distributions, indicating dissociable neural generator systems. Effects of the ionophores X537A and A23187 on GABA, glycine, and taurine release from chick retinal subcellular fractions.

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Late diastolic LV untwisting reduces with a gradual increase in the LA size in patients with cardiovascular risk factors, and may reflect the disease history of chronic LV diastolic dysfunction. The four TTR monomers associate around a central hydrophobic channel where two thyroxine molecules can bind simultaneously. This population is exposed to a series of hypertension risk factors, for instance: they are exposed to the stress associated with their studies, they are the target of publicitary promotion of fast foods, alcoholic drinks, smoking, and they share with the rest of the Puertorican population predisposition to diabetes mellitus. The general form of the SMTF is bandpass in nature, with a minimum modulation detection threshold in the region between 2 to 4 cycles/octave. Foot-shock stress-induced regional iron accumulation and altered iron homeostatic mechanisms in rat brain.

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The measurements were greater in children with unilateral cleft lip and palate. Furthermore, results are available which indicate that this is also valid for long-term storage. The results suggest that MS quantitation based on the analysis of Fc/2 (4) is accurate and gives results that are comparable to normal phase HPLC analysis of N-glycans (6).

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Podoplanin not only is highly expressed in lymphatic endothelium but also in other cell types, including sebaceous carcinoma cells. This presensor class facilitates self-selection among patients concerning their readiness to use real-time CGM. On both occasions, glomerular filtration rate and renal plasma flow were evaluated by inulin and paraaminohippuric acid renal clearances, and glomerular size-selective function was evaluated by the fractional clearances of neutral dextran macromolecules. Finally, we integrate recent ideas on cardiac development such as the ballooning and secondary/anterior heart field paradigms, showing how inflow/outflow patterning may interact with developmental mechanisms suggested by these models.

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Its effects on tumor growth were characterized using MTS assay, soft agar colony formation, and flow cytometry analysis. No dramatic effects of famciclovir were found on vertigo or dizziness. Both TK6 and WTK1 cells showed effective post-damage repair capacity in incubation time of 0.5 h to 1 h. However, while several pathways mediating the function of MIF in the immune system have been established, its role in pathogenic states such as autoimmune diseases has remained unresolved. A domino synthesis of benzoquinolinamide in the presence of iodine.

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The live pathology database of Montefiore Medical Center was searched for patients with AC2 endocervical swab specimens and SP Paps taken the same day. The prokaryotic expression vector for the extracellular domain of PD-L1 gene was constructed and protein expression in E.coli strain BL21(DE3) was determined. To determine in a meta-analysis whether the outcomes in men with localized prostate cancer treated with high-dose radiotherapy (HDRT) are better than those in men treated with conventional-dose radiotherapy (CDRT), by quantifying the effect of the total dose of radiotherapy on biochemical control (BC). Differences in maturity between the left and right sides were non-significant.

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To develop a robust 3D fast spin echo (FSE) T(2)-weighted imaging method with uniform water and fat separation in a single acquisition, amenable to high-quality multiplanar reformations. These calculations show that the potential impact of labelling and giving consumers the possibility to choose products with less salt is of public health importance. The in vivo potential of neural stem cells in the postnatal mouse brain is not known, but because they produce many different types of neurons, they must be either very versatile or very diverse. An analysis of variance was used to establish statistical significance.

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In many filaments a perforated sheet 20 nm in thickness was observed on the face of layer 2 which is toward the plasma membrane. A total of 1787 patients underwent endoscopic sphincterotomy during a period of 29 months. These results suggest that feedback control of ion channel expression may influence repolarization reserve.

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This intron resembles one inserted 21 nucleotides further downstream in a homologous TS gene (td) of Escherichia coli phage T4. The study broke many of the rules of trial design, not least by constant addition of further interventions and analyses, but this flexibility would, paradoxically, prove to be one of its greatest strengths. The main advantage of the developed method in comparison with other simpler and faster approaches is the accurate interference reduction in cases when the power line frequency deviates from the nominal 50 or 60 Hz.

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Department of Physical Medicine and Rehabilitation of a tertiary university hospital in Suwon, Korea. Delayed hemolytic transfusion reactions usually occur as a result of a secondary immune response with maximal hemolysis occurring seven days posttransfusion.

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The assessment of energy demand in the new Olympic windsurf board: Neilpryde RS:X. Here we show that SA can directly shut down the expression of the vir regulon. SQ 80,338 (10.0 micrograms/ml) prevented arachidonate-induced release of TXA2 from the isolated perfused guinea pig lung while SQ 24,775 (1.0 microgram/ml) antagonized the contraction of the isolated rat aorta induced by 9,11,AZO-PGH2.

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In vivo imaging and therapeutic treatments in an orthotopic mouse model of ovarian cancer. The production of ribosomes is ubiquitous and fundamental to life. We show here that primary fibroblasts derived from PML knockout mice are more sensitive to infection with encephalomyocarditis virus (EMCV), suggesting that the absence of PML results in an increase in EMCV replication. SHP there inhibits the expression of steroidogenic genes, on the one hand by inhibiting the expression of the nuclear receptors steroidogenic factor-1 and liver receptor homolog-1 (lrh-1), and on the other hand by directly repressing the transcriptional activity of LRH-1.

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Simultaneous separation of 12 o-, m- and p-positional enantiomers of tyrosine and fluorophenylalanine has been achieved by the use of optically active 18-crown-6-tetracarboxylic acid (18C6H4) as an additive in the background electrolyte. In conclusion, therefore, the different pharmacokinetic properties of the MDMA enantiomers may be caused by enantioselective metabolism by CYP2C19 and CYP2D6. The disassembly of promoter nucleosomes appears to be a general property of highly transcribed eukaryotic genes. Asynchronous e-learning is an appealing option for interprofessional education (IPE) as it addresses the geographic and timetabling barriers often encountered when organizing activities across educational programs. A multisyringe sequential injection method for monitoring water in the energy cogeneration system of a municipal waste incinerator.

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Pituitary adenylate cyclase-activating polypeptide (PACAP) acts on cortical precursor cells to trigger glial fibrillary acidic protein (GFAP) gene expression and astrocyte differentiation by stimulation of intracellular cAMP production. Does famotidine induce thrombocytopenia in neurosurgical patients?

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The reaction Hanger (proof of cephalin-cholesterol flocculation of the emulsion) in obstetrics Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics.

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To perform, in real conditions of prescription, the medico-economic evaluation of infliximab in severe RA. A pilot, open-labelled, phase II study using oral ribavirin in the treatment of patients with chronic active hepatitis B. The potential of targeted antibody prophylaxis in SARS outbreak control: a mathematic analysis. Benzothiadiazole (BTH) enhanced the accumulation of soluble and cell-wall-bound phenolics in strawberry leaves and also improved the resistance to powdery mildew infection under greenhouse conditions.

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Mixtures of Mycoplasma synoviae (MS) and MG could not be separated in this assay. Body fat, fat distribution and serum lipids, lipoproteins and apolipoproteins in African-American and Caucasian-American prepubertal children. Acute low cervical nerve root conditions: symptom presentations and pathobiological reasoning. The prognosis of patients with juvenile onset diabetes which require dialysis is poor, even if blood glucose is kept in the normal range by administration of exogenous insulin in standard techniques. The one who did not had hypogonadism, suggesting that testosterone may have a role in the regulation of breathing during sleep.

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To evaluate the factors involved in the development of consecutive exotropia (XTc), and the surgical procedures used for its treatment. And the ultrastructural changes of the pituitaries and the adrenal cortex cells were examined by electron microscope meanwhile. To study the expression and distribution of hepatocyte-enriched transcriptional factors during the differentiation of hepatocyte by rat bone marrow stem cells in vitro. Results showed that there is a right hemispheric disadvantage, in NAP but not AP musicians, in the retrieval of the verbal label to be assigned to the perceived pitch.

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As an initial case study, the potent isoform selective inhibitor N-(3-(aminomethyl)benzyl) acetamidine (1400W) of inducible nitric oxide synthase (iNOS) has been conjugated to a caging molecule 6-bromo-7-hydroxy-4-hydroxyquinoline-2-ylmethyl acetyl ester (Bhc). Using synthetic analogues of somatostatin in the complex treatment of bleedings from varicose esophagus and stomach veins in patients with liver cirrhosis But the restorative properties of this technique need to be observed on an in-vivo model. The incidence of blood parasites in wild birds is only briefly outlined as it is to be treated in detail in forthcoming papers.

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To facility life scientists in searching biological pathway data, we designed a biological pathway aggregator which aggregates various pathway datasets via the BioPAX ontology, a community-developed ontology based upon the concept of Semantic Web for integrating and exchanging biological pathway data. BioGlue and Peri-strips in lung volume nisamox 50 mg benadryl reduction surgery: pilot randomised controlled trial. However, these methods, primarily used for small-scale simulations, blur the fine details of the vortices, scale poorly to large-scale simulations, and do not easily enable isolating and tracking individual vortices. High miR-107 level expression can apparently induce cell cycle arrest at the G2/M phase and retard tumor growth in nude mice.

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Furthermore, high testosterone levels have been related to high oxidative stress. Danazol-beta-cyclodextrin binary system: a potential application in emergency contraception by the oral route. Prolonged incubation of porcine isolated coronary artery (PCA) to lipopolysaccharide (LPS) causes a moderate reduction in vessel constrictive responsiveness. A method for repeated evaluation of pulmonary performance in unanesthetized, unrestrained guinea pigs and tavanic dosage iv calculations its application to detect effects of sulfuric acid mist inhalation. At least three motifs, a His-rich N-terminal region, and the short CxxxC and MxxxMM sequences, are essential for the functionality of PpoB2, since site-directed mutagenesis of these motifs resulted in a non-functional protein.

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Fewer women than men undergo implantable cardioverter defibrillator (ICD) implantation for the primary prevention of sudden cardiac death. Images in Geriatric Cardiology - Myocardial Infarction by Enzymes With New Atrial Fibrillation. Exposure ihr sollte den tag nicht vor dem abend loben tabs guitar of MT resulted in a steady intracellular NO increase pattern under different concentrations with different values and has an increasing effect on eNOS concentration at a long time exposure.

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Exposure to environmental levels of lead (Pb) and manganese (Mn) has been associated with detrimental effects to neurodevelopment. After slow tissue freezing, specimens of testis and epididymis could be stored at -70 degrees C for at least norfloxacin dosage form solutions six weeks without any affect on EGFP fluorescence. Incidence and effects of West Nile virus infection in vaccinated and unvaccinated horses in California. Capnocytophaga species have been implicated as putative periodontal pathogens. Very limited information is available about the lipoprotein subclasses among populations living in South-East European region, and none for Serbia.

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The introduction of aggressive antihypertensive treatment has improved the renal prognosis during the last decades. Furthermore, familiarity with the environmental tibolone side effects uk cues/context was found to significantly enhance Fos expressions in dorsal striatum and dentate gyrus. Modulated repetition time look-locker (MORTLL): a method for rapid high resolution three-dimensional T1 mapping. We detected diverse coronaviruses by PCR in wildfowl and wading birds in England.

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Functional characterization of mutations involving the SCN5A-encoded cardiac sodium channel has sotalol 40 mg bijsluiter naproxen established the pathogenic mechanisms for type 3 long QT syndrome and type 1 Brugada syndrome and has provided key insights into the physiological importance of essential structure-function domains. The susceptibilities of 12 strains of enterococci and 10 stains of Listeria monocytogenes to N-formimidoyl thienamycin were determined by a standard broth dilution method. Apart from the pivotal action of Sry, many other genes are known to be involved in sex determination and subsequent differentiation. Incision induces the phosphorylation of CREB in the spinal cord, and the increase of p-CREB is mainly in the neurons.

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Matrix metalloproteinase citalopram antidepressant drugs inhibitor, CTS-1027, attenuates liver injury and fibrosis in the bile duct-ligated mouse. Three hitherto-unreported intragenic recombinant rotaviruses were identified.

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They also had reduced lateralisation in the theta band for longer inter-electrode distances, and increased frontal interhemispheric coherences in all frequency bands. Biostimulation of endogenous bacteria provides an efficient tool for the successful in situ remediation of mixed-waste sites, particularly those co-contaminated with heavy metals, nitrate and radionuclides, as found in the United States and other countries as environmental legacies borbalan fernandez dental of the nuclear age.

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The rare escitalopram overdose amount of xanax case of a 4 1/2-year-old girl suffering from a pathologic fracture of the tibia shaft due to a osteofibrous dysplasia is presented. Hepatitis A virus detection in food: current and future prospects. Correction of leg length discrepancy during hip arthroplasty is a technical challenge. melegueta could act as an antioxidant to preserve herbal preparations.

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Although the exact binding site of cruentaren remains undefined, inhibition was shown to occur by interaction with the catalytic F(1) domain. Importance of testing for usability when selecting and implementing an electronic health or medical record system. Spectral domain optical coherence tomography of the retina, 3T magnetic resonance imaging of the brain, spectrophotometric assessment of serum lactate levels. It generates classification rules, which are often smaller and easier to interpret. Learning and change among leaders celecoxib other drugs in same class of a professional nursing association.