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Aciklovir (Acyclovir)

Aciklovir (Zovirax) is an antiviral drug often used after a transplant. It is used to prevent and treat herpes infections of the skin, mouth, and mucous membranes; herpes zoster (shingles); chicken pox; and genital herpes. Aciklovir does not cure herpes, but it does relieve the pain and make the infection clear up faster. Aciklovir is taken by mouth, given by injection, or applied to the skin. The oral medication is available in 400- and 800-mg tablets and 200-mg capsules.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Aciklovir comes as a tablet, a capsule, and a suspension (liquid) to take by mouth. It also comes as a delayed-release buccal tablet to apply to the upper gum of the mouth. The tablets, capsules, and suspension are usually taken with or without food two to five times a day for 5 to 10 days, starting as soon as possible after your symptoms begin. When Aciklovir is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months. The delayed-release buccal tablet is usually applied with a dry finger as a one-time dose within 1 hour after itching, redness, burning or tingling cold sore symptoms begin but before the cold sore appears. Take or use Aciklovir at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take or use Aciklovir exactly as directed. Do not take or use more or less of it or take it more often or for a longer time than prescribed by your doctor.

Do not chew, crush, suck, or swallow the delayed-release buccal tablets. Drink plenty of liquids, if you have a dry mouth while using the delayed-release buccal tablets.

To use buccal Aciklovir, follow these steps:

  1. Find the area on the upper gum above your left and right incisor teeth (the teeth just to the left and right of your two front teeth).
  2. With dry hands, remove one delayed-release tablet from the container.
  3. Gently apply the tablet to the upper gum area as high as it will go on your gum above one of your incisor teeth on the side of your mouth with the cold sore. Do not apply it to the inside of the lip or cheek.
  4. Hold the tablet in place for 30 seconds.
  5. If the tablet does not stick to your gum or if it sticks to your cheek or the inside of your lip, reposition it to stick to your gum. Leave the tablet in place until it dissolves.
  6. Do not interfere with the placement of the tablet. Check to see if the tablet is still in place after eating, drinking, or rinsing your mouth.

If the delayed-release buccal tablet comes off within the first 6 hours of application, reapply the same tablet. If it still will not stick, then apply a new tablet. If you accidentally swallow the tablet within the first 6 hours of application, drink a glass of water and place a new tablet on your gum. If the tablet falls off or is swallowed 6 or more hours after application, do not apply a new tablet until your next regular time.

Avoid the following while you are using Aciklovir buccal delayed-release tablet:

  • Do not chew gum, touch, or press the buccal tablet after it has been applied.
  • Do not wear upper dentures.
  • Do not brush your teeth until it dissolves. If your teeth need to be cleaned while the tablet is in place, rinse the mouth gently.

Shake the suspension well before each use to mix the medication evenly.

Your symptoms should improve during your treatment with Aciklovir. Call your doctor if your symptoms do not improve or if they get worse.

Take or use Aciklovir until you finish the prescription, even if you feel better. If you stop taking Aciklovir too soon or skip doses, your infection may not be completely treated or may become more difficult to treat. The delayed-release buccal tablet is applied as a one-time dose.

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Slide enzyme-linked immunosorbent assay for the diagnosis of Babesia bigemina infection in bovines. Sheep were immunized with killed Salmonella enterica serotype Urbana cells and their sera were tested in various serological tests for antibody to Brucella sp., Yersinia enterocolitica O:9 and Escherichia coli O:157 H:7. To assess the efficacy of novel therapies for acute spinal cord injury (SCI), methods to evaluate accurately the effects of these therapies should be developed. These stage-specific changes corresponded to the major transitions of chromatin structure and function during spermatogenesis. Moreover, disease susceptibility was enhanced in the presence of non-myelin specific T-cells.

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Direct cost analyses of palivizumab treatment in a cohort of at-risk children: evidence from the North Carolina Medicaid Program. In this work, the isolation and characterization of AgaSGNH, a cDNA encoding a member of the SGNH-hydrolase superfamily from young leaf epidermis of the monocot Agave americana L., is reported. The design was validated through comparison with standard clinical pressure transducers in both bench top and clinical tests. Awareness and an understanding of the dying role have the capacity to guide the process. Postimmunization activity was unchanged for about half of the adult vaccine recipients.

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Growth and metabolic and hormonal profiles during transpyloric and nasogastric feeding in preterm infants. A transcription network analysis showed that Hsp47 expression was activated during breast cancer development and progression. Type 2 diabetes mellitus is associated with increased axial bone density in men and women from the Hertfordshire Cohort Study: evidence for an indirect effect of insulin resistance?

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In the field of human tissue-engineering, there has been a strong focus on the clinical aspects of the technology, i.e. A mixed monolayer of phospholipid and dye is chosen as a model system to test the feasibility of LB rotating transfer to fabricate continuous gradient structures, which is confirmed by the simulation and experimental results. A total of 34 men with benign prostatic hyperplasia (BPH) who have been on terazosin treatment (for the obstructive symptoms) were pathologically diagnosed with prostate cancer following surgery. Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells.

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