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Actalipid (Simvastatin)

A total of 406 individuals were randomized: 204 to Actalipid and 202 to placebo. We here report that low-dose Actalipid treatment inhibits excessive expression of monocyte tissue factor (TF) and reduces the persistent hypercoagulability state seen in cardiac transplant recipients.

Other names for this medication:
Simvastatin, Zocor, Actalipid, Lipex, Lipinorm, Lodales, Simcard, Simgal, Simvastatina, Simvor, Sinvacor, Sivastin, Vasilip, Zeid, Zocord, Zosta, Zostin,

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Actalipid is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It belongs to a group of drugs known as "statins. " It works by reducing the amount of cholesterol made by the liver. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

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Consequently, these descriptors may provide a basis for quantitative, noninvasive tear assessment. The most rigorous abstinence outcome reported with at least six months of follow-up was recorded. Studies directed at the synthesis of polycitone and storniamide natural products via vinylogous iminium salts and microwave accelerated Vilsmeier-Haack formylations are described.

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The type 1 transferrin receptor (TfR1) is well known as a key player in erythroid differentiation through its role in iron uptake. Experimental method for the conservative treatment of distal intraarticular radial fracture. Findings from this study provide an opportunity for greater understanding of the first mothering experiences of women aged more than 35 years, particularly women with significant career investment. These results suggest, however, that elevated levels of thyroid hormones also inhibit PRL release directly at the anterior pituitary level. Molecular modeling corroborated the electron microscopy data and further indicated that CD4-IgG2 but not CD4-gamma2 has significant potential to cross-link gp120-gp41 trimers on the virion surface, suggesting a mechanism for the heightened antiviral activity of CD4-IgG2.

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Two-month-old FVB/NJ male mice and age-matched Fmr1-KO mice were used in this study. We evaluated the performance and false positive rate of Mediace RPR test (Sekisui, Japan), a newly introduced nontreponemal test using a chemistry autoanalyzer. Understanding of the bone remodelling process has considerably increased during the last 20 years.

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krusei, and 6 other Candida species) were tested by using the National Committee for Clinical Laboratory Standards M27-A2 broth microdilution methods. Plasmatic concentrations of VIII: vWf greater than normal have not been shown to result in increased platelet adhesion or aggregation, so that is seems unlikely that the high levels of plasmatic VIII: vWf contribute directly to the pathogensis of retinopathy. Protein glycosylation can be vital for changing the function or physiochemical properties of a protein. Our findings indicate the presence of a novel role of AP-1 activity when HaCaT cells make a stratified epidermoid structure under 3D culture conditions.

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This paper presents new data on the tip of the tongue (TOT) phenomenon and its resolution in aging. Minimally invasive parathyroidectomy for primary hyperparathyroidism depends on accurate preoperative imaging.

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This review highlights effective phytotoxin-mediated strategies to distress, weaken or kill the plant host. Management-related issues, comorbidities and environmental factors are summarised. Thus, we present the first evidence that human HFs are direct targets of thyroid hormones and demonstrate that T3 and/or T4 modulate multiple hair biology parameters, ranging from HF cycling to pigmentation. Fracture mechanism of metal electrode integrated on a chip and fabrication of a poly(ethylene terephthalate) electrophoresis microchip.

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It is obvious that several of the immunosuppressive agents used today have disadvantageous influences on risk factors for CVD such as hyperlipidaemia, hypertension and post-transplantation diabetes mellitus (PTDM), but the relative importance of immunosuppressant-induced increases in these risk factors is basically unknown. Effects of mapracorat on mitogen-activated protein kinase (MAPK) phosphorylation were determined by cell based ELISA.

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Development of genome-wide microsatellite genetic resources in a commercially important African freshwater fish species - the Nile perch, Lates niloticus. Initial laboratory studies failure to demonstrate antinuclear antibodies. Characterization of the putative type III secretion ATPase CdsN (Cpn0707) of Chlamydophila pneumoniae. Our results will help in analysing and optimizing shoulder load in problematic functions both of work and leisure activities. Status dystonicus is a rare but life-threatening disorder characterized by increasingly frequent and severe episodes of generalized dystonia that may occur in patients with primary or secondary dystonia.

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In addition, some sequence polymorphisms have been considered to contribute to various diseases, but unambiguous correlations have not been established yet. Abnormal glycosylation can lead to protein malfunction, resulting in severe diseases. Special attention to the lower extremities of the younger trauma patient may be warranted. The pollination effectiveness of the commercially reared bumble bee Bombus impatiens Cresson, was compared in field studies to the honey bee, Apis mellifera L., for lowbush blueberry, Vaccinium angustifolium Ait. We also mapped the distribution of sites on the islet cells that exhibited direct (non-synaptic) responses to uncaging of excitatory and inhibitory transmitters.

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Our method facilitates laparoscopic rectal dissection while obviating the need for intracorporeal manual retraction. CRT was administered with a dual-energy (4 and 10 MV) linear accelerator.

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Resistant hypertension is defined as blood pressure not under goal despite being on at least three antihypertensives. The anti-TPO kits varied in terms of their imprecision and accuracy and in the density of coated antigen.

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Validity and internal consistency of the international knee documentation committee subjective knee evaluation form in children and adolescents. There is experimental evidence to support the notion that even mild degrees of acidosis, such as that occurring by ingestion of a high animal protein diet, induces some of these metabolic and endocrine effects. Our data suggest that adjuvant SBRT for resected pancreatic cancer can be achieved with minimal toxicity.

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Reduced graphs capture many important features of ligand-receptor interactions and, in conjunction with other whole molecule descriptors, provide an informative way to review HTS data. Adult clinical and immunologic outcomes of the national antiretroviral treatment program in Rwanda during 2004-2005. In contrast, although Lip-ETP delayed tumor growth, it did not decrease tumor size. Survival of patients receiving a liver transplant for hepatocellular carcinoma, and risk of tumor recurrence. This approach holds promise as a cost-effective means to integrate the physical and cognitive benefits of PA into high-risk schools.

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The functional Assessment of Cancer Therapy-Breast(FACT-B) was used to assess quality of life. Despite decades of study, only recently have receptors for several of these hormones been identified, revealing novel mechanisms for perceiving chemical signals and providing plant biologists with a much clearer picture of hormonal control of growth and development.

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Here, the CSCs and their counterpart non stem-like cancer cells (NSCCs) in human HT1080 fibrosarcoma cell line were sorted and labeled, then the two cell subtypes were mixed together and chosen separately to be irradiated via a proton microbeam. Neurons utilize only the full-length isoform, whereas Schwann cells, kidney cells, and blood lymphocytes only express the short form of L1.

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While most La is phosphorylated and resides in the nucleoplasm, a fraction is in the nucleolus, the site of ribosome production, although the determinants of this localization are incompletely known. At both examinations, similar abnormalities were found on five demanding neuropsychological tasks (language, concept shifting, abstraction, incidental memory, and verbal fluency), suggesting a generalized energetic deficiency. Human herpesvirus 8 viral FLICE-inhibitory protein inhibits Fas-mediated apoptosis through binding and prevention of procaspase-8 maturation. Pre-Irradiation of blood by gallium aluminum arsenide (830 nm) low-level laser enhances peripheral endogenous opioid analgesia in rats.

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Prevention of post-surgical abdominal adhesions by a novel biodegradable thermosensitive PECE hydrogel. Case-controlled study of OPTN sequence variants in individuals with or without glaucoma in populations of different ancestral origins and evaluate previous OPTN reports. Confocal microwave imaging for breast cancer detection: delay-multiply-and-sum image reconstruction algorithm. The main clinical presentations were dizziness, headache, vertigo, and visional dysfunction.

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We demonstrated the utility of live 3-dimensional transesophageal echocardiography in the assisted transcatheter closure of a mitral prosthesis paravalvular leak by Amplatzer occluder. Mist, zinc salt lozenges, echinacea extract, and vitamin C have no proven benefit in the treatment of acute bacterial rhinosinusitis. In this column, the author examines the trends of the midwifery model of care versus nonmedically indicated cesarean births and their effect on malpractice insurance rates. Prevention of infection in the elderly is far preferable to treatment of the disease, and can be promoted through precautionary measures when undertaking invasive procedures in older patients as well as through the administration of available vaccines. Unlabeled mycoplasma preparations competed with the binding of radiolabeled proteins, suggesting the involvement of a limited number of receptor sites on the host cells.

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Novel emission properties of melem caused by the heavy metal effect of lanthanides(III) in a LB film. Bovine apotransferrin was bound very weakly (1) by only a few isolates. The effect of AWYPLPP peptide on lung metastasis of HCC in vivo was evaluated in male nude mice with subcutaneously implanted HCCLM3 cells. Chromogranin A (CgA) is regarded as a major, nonspecific marker of neuroendocrine tumors (NET).

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Controlling the diameter and the length of Si probes can be realized by a selective vapor-liquid-solid (VLS) growth. A mixed-chimerism approach is a major goal to circumvent sustained immunosuppression, but most of the proposed protocols need antibody treatment or host irradiation. Brain targeting efficiency and direct nose-to-brain transport percentage for mucoadhesive microemulsion suggested an improved brain uptake following intranasal administration. Cardiac surgery in patients on dialysis: decreased 30-day mortality, unchanged overall survival. Bronchoalveolar lavage with diluted porcine surfactant for alveolar debris removal in newborns treated with mechanical ventilation

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At baseline and end of each phase of the study, fasting blood samples were collected to quantify plasma glucose levels, as well as serum insulin and lipid profiles. In addition, when dealing with the complexities of congenital heart disease, one must always be aware of the risks of pulmonary complications whether parenchymal or airway.

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One is the lack of MR images to be used to unmix signal sources of interest. This technique employs four enzymatic reactions in a single tube to monitor DNA synthesis. The method was examined by three sorts of simulated networks: those with linear, almost linear, and nonlinear network structures. To increase the satisfaction rate and responsiveness to the real needs of the staff, the current delivery system of wellbeing services in the TUMS should be redesigned by defining new wellbeing packages.

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Transmission electron microscopy revealed the presence of herpes-like virus particles in larvae. In vitro effects of platinum compounds on renal cellular respiration in mice. Subsequent computational analysis showed that these compounds have interactions with the Y3 binding site and their possible utility as an integrase inhibitor is discussed.

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Both Zevalin doses were preceded by an infusion of 250 mg/m(2) rituximab to clear peripheral B-cells and improve Zevalin biodistribution. Carbenicillin inhibiting the synthesis of peptidoglycan, a component of the bacterial cell wall, and lincomycin inhibiting the protein synthesis gave rise to nucleoid decay in cells from exponential cultures of Synechocystis 6803 and did not influence the nucleoids in cells from stationary cultures.

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The rats with established pneumonia were randomly divided into continuous and intermittent infusion groups with intraperitoneal azithromycin injection on a daily basis for 6 consecutive days, or for 3 consecutive days followed by a 3-day rest (which was repeated twice), respectively. Estimation of the total sulfur amino acid requirement and the effect of betaine in diets deficient in total sulfur amino acids for the weanling pig. The study was conducted on 97 patients with SNHL and 300 unrelated healthy Egyptian individuals, with normal hearing, as normal control subjects. Characterization of anion channels in the plasma membrane of Arabidopsis epidermal root cells and the identification of a citrate-permeable channel induced by phosphate starvation.

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The control sponges showed single capillaries and a thicker capsule. Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations. Furthermore, the treatment also caused an increase in antioxidant and a decrease in lipid peroxide levels in the granulation tissue. Simultaneous measurements of maximum walking time showed a similar variability, unlike the mean walking speed which turned out to be more stable. To investigate the influence of exercise and major competition on infectious episodes in athletes with spinal cord injuries (SCI).

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To evaluate the clinical efficacy and patient satisfaction of long-term danazol delivered vaginally as treatment for heavy menstrual bleeding. Participants in the treatment condition demonstrated greater improvements on tests of memory encoding and memory retention than the waitlist control group. Fibrous dysplasia covers a variety of rather different clinical pictures. State Board of Medical Examiners: Excerpts from Opinions of Legal Department. However, the miscellaneous component composition of this herbal medicine is not well known.

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In the previous paper of this series, we introduced the recursive approach and showed how correlations among particles of the same size can affect percolation. Increasing evidence suggests that tear hyperosmolarity is a central mechanism causing ocular surface inflammation and damage in dry eye disease. Due to stage of disease, age (median 82 years), or comorbidity they were considered unapt for surgery or conventional radiotherapy.

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In spite of the low energy used, the internal shocks are often painful and not well tolerated conducting to stop the use of these devices. Safety, simplicity and convenience of a modified prefilled insulin pen. Analysis of gamma-globulin mobility on routine clinical CE equipment: exploring its molecular basis and potential clinical utility. Constitutive expression of cyclin D1 in estrogen receptor positive MCF-7 and ZR-75 breast cancer cells (MCF-7(cycD1) and ZR-75(cycD1)) Increased the fraction of cells in S phase and reduced the G1 accumulation following retinoic acid treatment compared with control cells.

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Castration initially decreased nuclear AR staining in epithelial and stroma cells, in both tumor and non-malignant tissue, but after some months, it reappeared. The privacy of EPR in data communication and exchanging is provided by SSL/TLS-based secure communication. Large-scale glycomics for discovering cancer-associated N-glycans by integrating glycoblotting and mass spectrometry.

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Without this liner, the thermal performance of the casualty bag was very similar to the other two lightweight systems. Depression and comorbid illness in elderly primary care patients: impact on multiple domains of health status and well-being. Splenogonadal fusion is a rare congenital malformation characterized by intrauterine fusion of the spleen and gonad. Microrint pulmonary function testing in older adults with an intellectual disability.

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Public health and child and adolescent mental health services need to ensure that services and interventions fit to the purpose and are effective for children with limited intellectual functioning, and especially those living in poverty, as they are for other children. Actions to reduce re-admissions can be targeted to patient groups at risk, and should be aimed at the caring for chronic cardiovascular or pulmonary diseases, preventing complications and multiple ED visits, and ensuring continuity of care after discharge, especially for patients discharged on Friday. Parameter estimation and prediction were carried out using appropriate posterior simulation schemes based in Markov Chain Monte Carlo methods. The testicular abnormalities included disorganization of lobules and spermatogenic elements, inhibition of spermatogenesis, fibrosis of lobule walls, fatty necrosis, and, in one case, total disintegration of the elements in many lobules. An ancillary observation was that cellulose biosynthesis was unaffected in the double mutant, inconsistent with a predicted role for SGs in priming cellulose synthesis.

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We have tested the in vivo roles of MuRF1 and MuRF2 for muscle metabolism by using knockout (KO) mouse models. If all the elements are real with three independent parameters, this matrix is a 2 x 2 representation of the group Sp(2). Moreover, we demonstrate that RactIP can run incomparably faster than competitive methods for predicting joint secondary structures. Soft copies of 195 sets of CT examinations and concurrent chest radiographs in 180 paediatric patients (age 1 month to 15 years) were retrospectively reviewed. Usefulness of sputum galactomannan in diagnosis of pulmonary aspergillosis

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These data are the first to show a direct role for a specific phospholipid acyltransferase in regulating membrane trafficking and organelle structure. A slightly better outcome was reported for a combination of education and home physical therapy regimen than for patient education alone. Aspects of the Use of Angiotensin-Converting Enzyme Inhibitors and Calcium Antagonists in Treatment of Heart Failure in the Older Patient. Activity was found enclosed in immune complexes in which Fab/(Fab)(2) displayed a serine-like catalytic activity. French experience on IGRT: quality control, additional delivered dose, IGRT protocols and first clinical results

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Perceived psychological stress among high school basketball officials. Reactivation of this pathway may lead to altered osteoblast activity resulting in decreased bone mineral density, the pathological hallmark of osteoporosis.

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Identification of VPg-sbm-1 and P3-6k1-sbm-2 as independent pairs of genetic interactors between PSbMV and P. While findings are limited by the cross-sectional design of the study, given the known risks associated with comorbidity of the mood and anxiety disorders with CHD, findings reinforce the importance of comprehensive health assessment in Brazil. Aldehyde oxidase (AO) activity has been determined at 11 stages during the development of selected cin allelic homo-, hemi- and heterozygotes in Drosophila melanogaster.

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Definitive closure of a contained open abdomen is technically difficult due to the inability to obtain primary fascial suture. Treatment of the A549 cells with rIL-17 significantly increased VEGF-C expression, which was extracellular signal-regulated protein kinase 1/2 (ERK 1/2) dependent.

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Micromorphological study revealed the occurrence of opaque parts in decaying POM fragments and their individualization as fine, irregularly shaped opaque fragments in the soil matrix. voltammetric determination of piroxicam medication This article examines the demographic drivers underlying this rise, assessing the contribution of U.K. Eleven days later, she was readmitted because of a left hemianopsia. Therefore, uroflowmetry should not be performed in a position the individual is not familiar with. However several public-private initiatives have revived hopes of developing new products with growing involvement of industries in developing countries (India and Brazil) despite the high risks associated with fluctuating demand for medicines or funding shortages.

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Asthma is primarily an inflammatory disease but there are no simple tests to detect the accumulation of inflammatory cells and mediators. The results indicate that the small particles in sludge suspension had a strong deposit tendency on the alprazolam 2 mg dose membrane surface.

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Percentage body fat was lowest at ages 16-19 years among males and at ages 8-15 years among females. Systematic use of VCDs in elderly patients, with probable advanced limb atherosclerosis, is questionable. Thus, these results suggest that food intake and nutrient metabolism are coordinately regulated by the common signaling pathway of AMPK in the hypothalamus. Mutualistic interactions smooth functors vs differential forms cartan between plants and animals promote integration of invasive species into native communities.

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The exception was that the pituitaries of aged mice that were subjected to unusually high doses of GnRH continued to secrete higher levels of LH, whereas mibg scan medication contraindications for gabapentin the response of the pituitaries in younger mice plateaued after receiving 25 ng GnRH. Muti-criterion Optimization Algorithm for X-ray Phase Contrast CT imaging.

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Knockdown of HDAC6 significantly inhibited the proliferation and colony formation ability of A375.S2 cells, promoted cell arrest at G0/G1 phase and apoptosis. Transplantation of mouse induced pluripotent stem cells into the cochlea. Oral anticoagulant therapy safely prevented stroke in older patients with para que sirve denvar cefixima suspension atrial fibrillation.

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Sexually selected signals of individual dominance have profound effects on access to resources, mate choice and gene flow. In spin systems with considerable anisotropy, the microwave pulses excite only a fraction of the electron paramagnetic resonance (EPR) spectrum and the resulting orientation selection needs to be explicitly taken into account if a meaningful distance and orientation is to be determined. Magnetic resonance imaging (MRI) revealed bone marrow edema and hyperintensity of the odontoid process, but there were no indications of fissures or fracture lines. These misclassification characteristics must be kept in sulfatrim pediatric side effects mind when interpreting severity results based on police data. All 20 patients underwent lumbar spine CT on the 320-detector row scanner (Aquilion One, Toshiba).

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Plasma concentrations of 15alpha-P also responded to cinie 50 mg tablettalk far lower doses of GnRH I and GnRH III than any other steroid previously investigated in lampreys. Most significantly, there was no difference in the frequency of post-procedure infection between the groups.

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Identification of the CD40 (CD154) ligand expression on the surface of conglomerate platelet-monocyte in children with the metabolic syndrome The focus of the World Health Day 2010 is on urbanization and health. The ratio of PPRL to isoform 1 was obviously reduced after ovariectomy (OVX), and lamotrigine cost australian it recovered with estrogen replacement.

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Laser-mediated cartilage reshaping with feedback-controlled cryogen spray cooling: biophysical properties and viability. However, CGH cannot be relied on to detect 20q deletions, which torgyn drug testing are the most frequent cytogenetic abnormality in PV. On average the plateau began about 4 years prior to the clinical diagnosis of AD and ended with a decline that probably contributed to the clinical diagnosis of AD. To assess whether the use of a combined protocol including conventional magnetic resonance imaging (MRI), diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), and proton MR spectroscopy (MRS) could detect pathological findings in a piglet model 7 hours after HI.