FREE
SHIPPING!

on all orders above $300.00

FREE Pills!

VIAGRA PILLS

for free with every order

OUR DRUG PRICES are

70%

Less than in your
local pharmacy

Search by letter:

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Enter coupon: (if you have one)

Amantan (Amantadine)
+ BONUS
 
Amantadine

A double-blind, cross-over comparison of the effects of Amantan or placebo on visuomotor and cognitive function in medicated schizophrenia patients. The results suggest that drugs which influence central histaminergic mechanisms are effective only in modifying the stereotyped behaviour induced by the indirectly-acting DA agonist Amantan, and fail to modify the stereotyped behaviour induced by apomorphine, a directly-acting DA agonist.

Other names for this medication:
Amantadine, Symmetrel, Aman, Amantadina, Amantan, Amixx, Antadine, Lysovir, Mantadan, Mantadix, Protexin, Symadine, Tregor, Viregyt, Virosol,

Similar Products:
Largopen, Hydertan, Biogel, Neuros, Anxiron, Citol, Flavix, Losita, Venlafaxine, Victadol, Bicor, Ciprofloxacina, Zumo, Zoton, Chear, Lipitor, Omacillin, Westoxetin, Zocord, Vistaril, Meixil, Gabaran, Miracid, Motivan, Zytram, Logastric, Dosier, Herplex, Trangorex, Soviclor, Letop, Ovelquin, Nexe, Kemadrin, Grunamox, Loortan, Funginoc, Cambia, Amoxivet, Omalcer, Lamotrix, Conmycin, Armolev,

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

amantan multiple sclerosis symptoms

Early in stand development, spatial pattern was more important than the symmetry of competition in determining the degree of size variation within the population, but after plants grew and competition intensified, the size asymmetry of competition became a much more important source of size variation. Porcelain may fracture or chip if exposed to any traumas and can be repaired by using a resin composite. The effect of vitamin B12 on the anemia and combined system disease of addisonian pernicious anemia. Starting from vinyl pyranoses an iron-catalyzed tandem isomerization-intramolecular aldolization reaction was developed to prepare cyclohexenone derivatives bearing substituents on the double bond, and it has been applied in a short synthesis of 4-epi-gabosines A and B, from d-glucose. Remodelling of action potential and intracellular calcium cycling dynamics during subacute myocardial infarction promotes ventricular arrhythmias in Langendorff-perfused rabbit hearts.

amantan multiple sclerosis symptoms

We present the case of a 52-year-old man with steroid-dependent ulcerative colitis, needing immunosuppressive therapy with azathioprine. This article reviews the current understanding in hand tissue engineering before focusing on the potential for scaffold topographical features on micro- and nanometre scales to achieve better functional regeneration of individual and composite tissues. Depression and hostility as part of the bipolar spectrum - in the context of early-onset drug dependence, work and social/leisure problems - appear independently associated with suicidal ideation. We performed two sets of molecular dynamics simulations for the unbound receptor and ligand structures of 17 protein complexes and applied shape-driven rigid body docking to all combinations of representative snapshots. VIII: vWf is distributed in plasma, platelets and subendothelium, though the contributions of each pool to normal hemostasis is unknown.

amantan multiple sclerosis symptoms

This report aims to review the literature regarding several members of the nucleotide-binding domain, leucine-rich repeat-containing receptor (NLR) family of pattern recognition sensors/receptors that serve as checkpoints for inflammation. Insecticidal crystal protein CrylCa7 from Bacillus thuringiensis which is highly toxic to Spodoptera exigua, an important agricultural pest in China, and we mutated this toxin by over-lapping extensive PCR method in different domains to obtain 11 chimeric mutants. Recently, genome-scale methods have been brought to bear on this problem.

amantan multiple sclerosis symptoms

Our findings suggest that physicians selectively target treatment for their patients, and these evidence-based therapies can be safely administered to ACS patients in clinical practice. The diverticulum of the urethra of the woman is an ignored affection her treatment is surgical.

amantan multiple sclerosis symptoms

Effect of Intraoperative Dexmedetomidine on Post-Craniotomy Pain. This result also suggests the importance of fragmenting cRNA down to lengths of 50-200 bases before the hybridization process.

amantan multiple sclerosis symptoms

In addition, mRNAs are in continuous flux between polysomes and cpSGs during stress. Minimally invasive procedures seem to lower the threshold for referral for surgical therapy. Endomyocardial fibrosis mimicking a dilated cardiomyopathy in a child. Our findings demonstrate early filtering of irrelevant information under increased attentional demands, thus supporting models that assume a flexible mechanism of attentional selection, but reveal important functional asymmetries across the VF. Anti-Inflammatory effects of low-level laser therapy (660 nm) in the early phase in carrageenan-induced pleurisy in rat.

amantan multiple sclerosis symptoms

Screening of target proteins interacting with dexamethasone derivates in vivo Two new examples of Dy6 cyclic coordination clusters have been synthesised in order to discover how the toroidal moment in such a motif can be tuned and optimised. The use of adjuvant cisplatin-based therapy did not show a survival advantage in the Adjuvant Lung Project Italy study but did in the International Adjuvant Lung Trial, creating controversy in the routine implementation of adjuvant therapy in all patients. Fresh-frozen plasma (FFP) is given to patients across a range of clinical settings, frequently in association with abnormalities of standard coagulation tests. Because cells constantly interact through gap junctions to coordinate tissue functions and homeostasis, we hypothesized that increasing cell-to-cell communication, via genetically engineering cells to overexpress gap junction proteins, could enhance cell differentiation in the interior regions of 3D tissue equivalents, thereby increasing the ability to regenerate larger and more uniform volumes of tissue.

amantan multiple sclerosis symptoms

Development of a standard case definition and assessment of the best approaches for local and national neonatal herpes surveillance may improve performance of such reporting. Regulation, legal requirements and calibration procedures are different in European member states. Periodic leg movements during sleep often occur in narcoleptic patients. We also studied the gene expression of mRNA and protein in these key BER enzymes with real time-polymerase chain reaction (RT-PCR) and western blot analysis. Using the data of the 1-stage putty-wash impression as reference, the reproduction of the finishing line was measured 3-dimensionally.

amantan multiple sclerosis symptoms

Cells (10(6)) were seeded onto EDC cross-linked collagen sponges and implanted in 30 immunodeficient mice. Alpha-Difluoromethyl-DOPA (DFMD), a drug that inhibits the conversion of 5-HTP to L-5-hydroxytryptamine (5-HT) abolished the nephrotoxicity of 5-HTP. The bmpA/B mutant was also impaired in the induction of NF-kappaB and p38 MAP kinase signaling pathways in synovial cells, which were activated by non-lipidated BmpA.

amantan multiple sclerosis symptoms

RTX treatment may induce sustained remission in patients with GD with low TRAb levels. Cough in children with congenital central hypoventilation syndrome. The intracellular levels of antioxidant and free radical scavenging enzymes are gradually altered during the aging process. In molecular biology, the issue of quantifying the similarity between two biological sequences is very important.

amantan multiple sclerosis symptoms

The patient survived severe encephalopathy with a locked-in syndrome. Here, we established Xenopus A6 epithelial cell transfectants expressing GFP-fused full-length APC (GFP-fAPC) or truncated APC lacking the COOH-terminal PDZ-binding motif TSV (GFP-APC(DeltaTSV)). Testicular volume and sperm density were inversely correlated with basal and stimulated FSH and LH levels. Here we show that these genes all encode small polypeptides that share the common structural features of an N-terminal putative signal sequence, a highly divergent intermediate region and a conserved 60 amino acid C-terminal domain containing 12 conserved cysteine residues.

amantan multiple sclerosis symptoms

These characteristics concerning the viscosity are quite different from those for a semi-dense dispersion composed of rodlike particles with a magnetic moment along the particle direction. Both chondroitin-sulfate and hyaluronic acid were found to be transported to the interior of the cultured cells and then degraded.

amantadine uses parkinson's symptoms early

  • amantadine mechanism of action animation movie
  • amantadine symmetrel dosage form
  • main site of action of amantadine hcl
  • amantadine dosing for influenza
  • amantadine uses off label
  • amantadine uses parkinson's symptoms early
  • main site of action of amantadine hydrochloride
  • amantadine adhd children
  • amantadine hydrochloride capsules usp monograph testing
  • amantadine 100mg capsules p.o. b.i.d
  • amantadine for tbi treatment research
  • amantadine cost uk visa
  • amantadine hcl bcs classic
  • amantadine bauru recipe
  • amantadine concussion headache symptoms
  • amantadine side effects hair loss
  • amantadine cost uk tv
  • amantadine drug group meetings
  • amantadine more drug uses
  • amantadine syrup for dogs
  • amantadine for concussion symptoms
  • livedo reticularis amantadine treatment for tbi
  • amantadine parkinson's tremor treatment
  • borna virus amantadine hcl
  • amantadine cause live do reticularis image
  • amantadine drug monograph acetylcysteine
  • amantadine for tbi treatment michigan
  • amantadine sulfate 100 mg
  • amantadine and tramadol side effects canine
  • amantadine for ms fatigue reviews on hydroxycut
  • lysosomotropic amantadine dosage
  • amantadine drug action of ambien
  • main site of action of amantadine poisoning
  • amantadine symptoms of withdrawal
  • amantadine hcl msds liquid
  • gintoki and jirocho vs amantadine
  • amantadine costco photo
  • amantadine hcl classification
  • amantadine drug study scribd app
  • side effects of amantadine symmetrel
  • amantadine hydrochloride usp monograph calcium
  • amantadine drug study scribd documents
  • amantadine drug study scribd
  • amantadine drug for adhd
  • side effects of amantadine hcl msds
  • amantadine dosing for concussion
  • drug amantadine
  • amantadine uses ms
  • amantadine adhd dose
  • amantadine dosing for tbi
  • pro amantadine uses
  • tablet amantadine hcl
  • amantadine overdose
  • amantadine treatment for children
  • amantadine hcl msds info
  • amantadine 100 mg skin rash
  • amantadine syrup uses
  • amantadine used for opiate withdrawal
  • livedo reticularis amantadine treatment for parkinson's disease
  • amantan multiple sclerosis symptoms
  • amantadine price in pakistan iphone
  • amantadine mechanism of action parkinson's treatment

amantan multiple sclerosis symptoms

Does prostate growth confound prostate specific antigen velocity? Effectiveness of p38MAPK activity during drug resistance against HepG2 Diazonamide A is highly effective at blocking spindle assembly in mammalian cell culture and does so through a unique mechanism. To evaluate the safety and efficacy of intravenous (IV) sodium ferric gluconate complex (FG), oral ferrous sulfate, or no iron to increase hemoglobin (Hb) in anemic cancer patients receiving chemotherapy and epoetin alfa. By fusing GFP protein to FHbs, we determined that FHb1 and FHb2 are located in the cytosol and mitochondria, respectively.

amantan multiple sclerosis symptoms

Atrazine chlorohydrolase (AtzA) was discovered and purified in the early 1990s from soil that had been exposed to the widely used herbicide atrazine. BR was useful as infusion fluid and CPB priming solution for infants and children who underwent open-heart surgeries, and reduced the administration of sodium bicarbonate during surgery.

amantan multiple sclerosis symptoms

In total 185 British adults, recruited by a market research company, completed a four-part questionnaire, lasting about 20 minutes. Dynamic-mechanical properties of a novel composite intervertebral disc prosthesis.

amantan multiple sclerosis symptoms

Limited access to iodized salt among the poor and disadvantaged in North 24 Parganas district of West Bengal, India. To understand the structural basis of the nephrotoxicity induced by AAs, the ALI-N(6)-dA and ALII-N(6)-dA lesions are systematically studied using computational methods. CT scan or MRI are the standard imaging studies for lymph node dissemination, whereas bone scan continues to be the routine test for bone dissemination.

amantan multiple sclerosis symptoms

Univariate and bivariate sensitivity analyses and Monte Carlo simulations were performed to assess model robustness. Paracoccidioides brasiliensis causes infection through host inhalation of airborne propagules of the mycelial phase of the fungus, which reach the lungs, and then disseminate to virtually all parts of the human body. Although the in vivo role of Dectin-1 has still to be fully elucidated, there is emerging evidence that this receptor plays a role in the inflammatory response to pulmonary fungal pathogens and that it is involved in certain autoimmune and respiratory diseases. The diagnosis was confirmed by a histological study following autopsy.

amantan multiple sclerosis symptoms

Intrinsic defect introduction into a 3-dimensional photonic crystal is also proposed. Results from both simulations and real microarray data show that the proposed scheme is promising for identifying cycling genes and revealing underlying gene expression profiles.

amantadine uses ms

The nauplius VI of both species undergoes a conspicuous change before metamorphosis into cyprid stage. When given alone, the gN DNA vaccine did not induce detectable gcII specific antibody even though in vitro gN expression was confirmed by the formation of gM/gN complex in FSK cells using a gN-specific monoclonal antibody 14-16A. This provides an appropriate riate intra-operative 3D visualization without pre oroperativeintra- perative imaging. This colour change was consistent with the characteristics of a quinone, 1-phenyl-2,3-benzoquinone, which could arise from the oxidation of 2,3-dihydroxybiphenyl.

amantadine used for opiate withdrawal

The effects of activating prior topic and metacognitive knowledge on text comprehension scores. Yet, there is still little documentation on how distinct predator foraging types control biodiversity, food-web architecture and ecosystem functioning. A 58-year-old man who required long-term hemodialysis was referred to our institution for the management of life-limiting intermittent claudication of the right lower extremity. Both children can now tolerate oral diet and their speech and language development is in line with their overall developmental level.

amantadine adhd children

However, no significant survival difference is seen between the different type 1 subgroups. Nano-manipulation of single DNA molecules based on atomic force microscopy.

amantadine more drug uses

However, to our knowledge, no previous studies have explored the consequences of using the pooled-islet design. Importantly, none of the identified SNPs was exclusively associated with affectation status.

amantadine hcl bcs classic

Long-term behavior change and health improvements were not examined by this review because of a lack of long-term follow-up in the literature. The author presents a review of research in the area of intimate partner violence in the rural setting. We establish the physiological significance of the interlocked positive feedback loops by showing that the levels of WC-1 and WC-2 determine the robustness and stability of the clock. An Arabidopsis T-DNA null mutant named ccomt 1 was identified and characterised.

amantadine drug study scribd app

The phosphorylation state of WASP and WASP-interacting proteins was determined in osteoclasts treated with osteopontin or expressing either constitutively active or kinase-defective Src by adenovirus-mediated delivery. Functional analysis of the sheep Wilson disease protein (sATP7B) in CHO cells. Hypertension is more common in men than in women of the same age.

main site of action of amantadine hydrochloride

The most common angiographic finding is a relatively smooth or slightly irregular tapered arterial narrowing. The majority of known bacteriophages have long noncontractile tails (Siphoviridae) that serve as a pipeline for genome delivery into the host cytoplasm.

amantadine dosing for concussion

Health care metrics, such as readmission rates, are being scrutinized to improve quality and decrease cost of care. Furthermore, 3D-QSAR and MFA calculations were scrutinized to quantify the role of weak interactions in binding affinity and drug efficacy. The authors have examined Italian and international approaches to the health surveillance of subjects with past occupational exposure to asbestos, with special emphasis on the practices adopted by some Italian regional governments. Median facial cleft with a frontoethmoidal encephalocele treated with craniofacial bipartition and free radial forearm flap: a case report. This shift in the NMDA receptor mRNA levels may be a possible molecular mechanism contributing to alterations in cognitive behavior during normal aging.

amantadine overdose

In addition, mineralized nodule formation, which was examined by alizarin red staining, was also inhibited in HDPCs by the same treatment. The case was managed conservatively, and serial echocardiographic follow-up showed gradual reduction in size until ultimate disappearance of the mass 1 month later. Antiretroviral therapy (ART) has been more accessible in these countries. The structure has similarities with that of the secretin protein, PilQ, which mediates the transition of type IV pili across the outer membrane. Follow-up of AFP levels in metastatic gastric cancer patients with elevated AFP levels may allow prediction of early treatment response and could be more useful than the CEA marker for follow-up in response evaluation.

amantadine hcl bcs classic

The influence of the antigen density and other factors on the serum titer in the agglutination-lysis-test for leptospirosis. Coronary angiography and 16-slice computed tomography revealed an abnormal origin of the right coronary artery from the left sinus of Valsalva, coursing between the aorta and the pulmonary trunk and then giving origin to the left circumflex coronary artery. Living donor liver transplantation (LDLT) is now widely performed for patients to resolve the critical shortage of organs from cadavers. Realizing that education and awareness are paramount in making clinical trials available to improve overall accrual rates, we sought to create a clinical trial navigation service to improve the accessibility of cancer clinical trials in Florida for physicians and patients.

amantadine drug group meetings

This study demonstrates, for the first time in vivo, a negative feedback between sPLA2 and cPLA2 and assigns opposing roles for these enzymes in asthma pathophysiology: sPLA2 activation induces production of the bronchoconstrictor CysLT and suppresses cPLA2 expression and the subsequent production of the bronchodilator PGE2. The frictional ratios (f/f(0)) of the two proteins indicated that gp14 has a more elongated shape than gp13. The present study has significant implications for informing individuals regarding medical procedures. Therapeutic plasma exchange (PE) or plasmapheresis is the treatment of choice in many neurological disorders.

amantadine adhd children

Adhesion-complex proteins including M-cadherin, beta-catenin, and p120-catenin accumulated at the leading edge of lamellipodia, which contains the presumptive fusion sites of the plasma membrane, in a lipid raft-dependent fashion prior to cell contact. Assessment of intra- and interobserver variability of pulmonary vein measurements from CT angiography. A Remember-Know paradigm was used to examine the cognitive resource requirements of recollection and familiarity memory processes at retrieval.

tablet amantadine hcl

Although the commonest cause of cliteromegaly is hormonal, a metastatic carcinoma should be considered as part of the differential diagnosis in the elderly female. Fractionation and Ca uptake studies on membranes of rabbit longitudinal and circular intestinal smooth muscle. Defective bone formation (osteodystrophy) was considered a secondary process resulting from inflammation of osteochondral complexes, marrow, and periosteum.

amantadine syrup for dogs

Our findings indicate that the structural dominance of the cortical shell and centrum alternate depending on the location within the vertebral body. Estrogen (E) exerts its function by binding to two intracellular estrogen receptors, ERalpha and ERbeta. Design and implementation of a home-based exercise program post-hip fracture: the Baltimore hip studies experience. We used a phantom to evaluate the errors introduced during navigation. We assessed subjective sleep reports and associated them with multiple indicators of psychosocial adaptation in 240 women with Stage I-III BCa before they had begun adjuvant treatment.

amantadine symptoms of withdrawal

The purpose of this article is to provide a short, balanced review of the literature concerning creatine monohydrate in the treatment of ALS and related neurodegenerative diseases. Tissue engineered skin models with well-developed basement membrane structures thus appear to be useful tools for in vitro mechanistic studies of SM vesicant activity and development of preventive/therapeutic approaches for SM pathology. The patient, a victim of a collision with an intoxicated driver, arrived at the hospital as I was caring for another patient who was undergoing his tenth admission for detoxification. Radical prostatectomy is an effective form of therapy for patients with clinically localized cancer of the prostate.

main site of action of amantadine hcl

We present the neurological and neuropsychological features of a patient with partial cerebellar agenesis (TZ), together with SPECT perfusion and fMRI activation during a finger tapping task. The studies were obtained from PubMed during 2008 and 2009 using the following key words: chronic obstructive pulmonary disease, COPD, adherence, controller medication, and persistence. Free I(2) formed in situ and presented to semen is an extremely potent spermicide.

amantadine side effects hair loss

Furthermore, the muscle production of arachidonic acid metabolites during exercise depends on the intensity of the exercise. Then, various polymers such as poly(ethylene glycol) (PEG), poly(tetrahydrofuran glycol) (PTG), poly(propylene glycol) (PPG) and poly(dimethylsiloxane) (PDMS) were grafted on the silanized stainless steels. Conformational properties of cis- and trans-N-Cyclopropylformamide studied by microwave spectroscopy and quantum chemical calculations. Because aberrant FGF signaling and Msx2 activity result in similar craniofacial skeletal defects and because Msx2 is an established regulator of osteoblastic gene expression, here we investigate Msx2 as an additional mediator of PC-1 gene expression.

amantadine drug study scribd documents

Insulin signalling at target tissues results in a large array of biological responses. Oral administration of PL is an effective systemic chemophotoprotective agent leading to significant protection of skin against UV radiation. Erlotinib, at clinically achievable dosages, repressed BEAS-2B cell growth, triggered G1 arrest, and preferentially reduced cyclin D1 protein expression and transcriptional activation.

side effects of amantadine hcl msds

Osteoblast differentiation profiles define sex specific gene expression patterns in craniosynostosis. The data obtained in this study might contribute to a better understanding of the pathophysiology and assessment of bleeding risk in OLT. Bilateral basal ganglionic lesions due to transdermal methanol intoxication. Recently developed candidate reference methods promise to yield greatly improved standardization for the measurement of glycohemoglobin. In the developing brain, Prdm8 expression was observed in postmitotic neurons in the intermediate zone and the cortical plate.

amantadine concussion headache symptoms

Targeted salmon gene array (SalArray): a toxicogenomic tool for gene expression profiling of interactions between estrogen and aryl hydrocarbon receptor signalling pathways. Hydrogel nerve conduits produced from alginate/chitosan complexes. Advanced clear cell renal cell carcinoma is characterized by extensive intratumoral genomic heterogeneity and branched as well as convergent evolutionary traits with genomically different subclones evolving in parallel in the same tumor. Kikuchi-fujimoto disease associated with myasthenia gravis: a case report.

Testimonials
Best
 Show Hide 
amantadine for concussion symptoms 2013-04-10

The possibility of tenofovir monotherapy as a rescue therapy in patients with chronic hepatitis B Traditional anterolateral approaches have pneumocystis carinii treatment dose acyclovir divided the anterior portion of the gluteus medius and minimus and potentially jeopardized the superior gluteal nerve. The proposal for increasing the security in Computerized Adaptive Tests that has received most attention in recent years is the a-stratified method (AS - Chang and Ying, 1999): at the beginning of the test only items with low discrimination parameters ( a ) can be administered, with the values of the a parameters increasing as the test goes on. Nematode diversity did not change since the start of the extraction activities but nematode community composition changed significantly. Triple drug therapy with rifampicin, ethambutol hydrochloride and clarithromycin.

amantadine uses ms 2011-06-02

Cryosurgery combined with Iodine-125 seed implantation in the treatment of unresectable lung cancer. MEDICAL PROGRESS: Current Methods for Study and Treatment of Sterility. It has been shown that a 100-fold dilution vitobel b12 injections can be used to measure concentrations of below 1 mBq L(-1), whereas a 20-fold one can be used to reach concentrations of below 0.06 mBq L(-1).

amantadine syrup uses 2016-02-04

In this study, we have analyzed the morphogenesis of the birnavirus infectious pancreatic dutasteride online bestellen in suriname necrosis virus throughout the infective cycle in CHSE-214 cells by using a native agarose electrophoresis system. Nuclei were present in both the mother cell and the emerging bud, consistent with Sec14p regulation of the cell cycle subsequent to anaphase but prior to cytokinesis/septum breakdown.

amantadine drug monograph acetylcysteine 2018-04-23

SEMSs for benign esophageal manfaat telfast 120 mg fexofenadine disorders in children can be used safely and effectively in selected cases, including esophageal anastomotic strictures, esophageal leaks following primary surgery, or perforations postdilatation. Second, a needle must be guided under constant visualization toward the targeted tissue. cerevisiae single-gene-deletion mutants to identify those that have decreased or increased growth, relative to wild type, after exposure to sodium arsenite (NaAsO(2)).

amantadine and tramadol side effects canine 2010-12-29

We show that the tools are reliable in aquatic environments to assess the speciation of ratiopharm diclobene 100 mg dissolved contaminants and hence provide a good insight into the potential bioavailability of contaminants. Our approach introduces a new concept for classifying building blocks of proteins based on thermal fluctuations.

amantadine sulfate 100 mg 2010-01-15

Dynamic modelling of a traditional African chicken production system. Invasion of the maternal decidua trisul medication list by extravillous trophoblast is an important process for embryo implantation and placentation in humans.

amantadine cost uk visa 2012-06-16

In both the cases a proximal row carpectomy was performed with excellent outcome. Noise exposure is one of the most common causes restream reviews of hearing loss. The TCT motif is required for transcription of ribosomal protein gene promoters.

side effects of amantadine hcl msds 2017-08-08

Failure of stimulated skeletal muscle mainly amocla safe for pregnancy contributed by passive force: an in vivo rabbit model. In contrast, the selectivity improved at pH 2.5 but decreased at pH 3.8 upon the addition of 2 M urea. The reasons are, however, unclear and further studies are necessary.