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Simcard (Simvastatin)

Ten non insulin-dependent diabetics in satisfactory metabolic control but with high cholesterol levels were treated with Simcard. Inflammatory predictors of mortality in the Scandinavian Simcard Survival Study. Simcard induces activation of the serine-threonine protein kinase AKT and increases survival of isolated human pancreatic islets.

Other names for this medication:
Simvastatin, Zocor, Actalipid, Lipex, Lipinorm, Lodales, Simcard, Simgal, Simvastatina, Simvor, Sinvacor, Sivastin, Vasilip, Zeid, Zocord, Zosta, Zostin,

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This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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Cloning EcoRI (or EcoRI)-generated fragments of deoxyribonucleic acid from several sources into the single EcoRI site in plasmid pPL603, with subsequent selection of transformants of media containing 10 micrograms of chloramphenicol per ml, permits the identification of restriction fragments that promote expression of the chloramphenicol acetyltransferase gene. The results show that g(F) and p(E) can reproduce the g and p obtained using a given count center. The transcription factor WRKY70 was previously reported to be a common component in salicylic acid (SA) and jasmonate (JA) mediated signal pathways in Arabidopsis. Temporomandibular disorders and facial pain: a psychophysiological perspective.

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In support of the data obtained using nanobodies, a single point mutation (P325A) involving the C-terminal residue of IRF-1 has been identified, which results in greater transcriptional activity and a significant increase in the rate of degradation. Presence and species identification of the gapeworm Mammomonogamus laryngeus (Railliet, 1899) (Syngamidae: Nematoda) in a semi-wild population of Sumatran orangutan (Pongo abelii) in Indonesia. One child showed auditory neuropathy only on one side with normal hearing thresholds on the contralateral ear. Intermittent hypoxia causes a suppressed pituitary growth hormone through somatostatin.

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The first system with reverse osmosis system can be used in areas where desalination is required in order to be able to use the recycle water for irrigation of all crops. Novel technology to provide an enriched therapeutic cell concentrate from bone marrow aspirate. These results demonstrate that collagen-chondroitin sulfate scaffolds are good substrates for artificial cornea construction with good resilience, long-term culture capability, and handling properties. We report an unusual case of SEA that developed from preceding SEH, posing a diagnostic challenge to physicians.

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A functional magnetic resonance imaging technique based on nulling extravascular gray matter signal. First-person experience and yoga research: studying neural correlates of an intentional practice.

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The pathogenesis of natalizumab-associated PML may be different from that of PML not associated with the drug. Altogether, we report previously undescribed complexity of the COPII coat in the ancient eukaryotic ancestor and speculate on models for the evolution, not only of the complex, but its relationship to other protocoatomer-derived complexes. Commercial internet-based companies offer genome-wide scans to predict the risk of common diseases and personalize nutrition and lifestyle recommendations.

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Aerolysin, the hemolytic toxin produced by Aeromonas hydrophila, has been purified by a combination of salt fractionation, gel filtration, and ion-exchange and hydroxyapatite chromatography. We use an artificial neural network to model the dynamics of complicated gene networks and to learn their parameters. Perforator flaps have been increasingly used in the past few years for trauma and reconstructive surgical cases. The aim of this study was to analyze circadian variation of myocardial infarction size and in-hospital mortality in a large multicenter registry.

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7-trifluoromethylquinoline-functionalized luminescent photochromic spiropyran with the stable merocyanine species both in solution and in the solid state. Mimic vessel walls are formed by tumor cells, not by endothelial cells. Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. While not well known in the West, Taiwan has a substantial indigenous population, and this population has rapidly developed alcohol problems. Together, these findings indicate that PRL employs multiple mechanisms to promote mammary tumorigenesis.

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In this paper, we describe a radial basis function neural network (RBFNN), whose hidden centers and basis function widths are optimized by a genetic algorithm (GA), for the purpose of predicting three dimensional spatial distance location from primary sequence information. Regulation of various proteolytic pathways by insulin and amino acids in human fibroblasts. A multipurpose frame retractor for treatment of perforated gastroduodenal ulcers The purpose of this study was to define the natural history of post radical prostatectomy incontinence using an objective quantitative tool, the 1-hour standard pad test. The peptides were removed from the context of the phage and placed on a pegylated tetrameric scaffold.

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Motor symptoms, however, are less likely to resolve following nerve release. Gait unsteadiness and fall risk in two affective disorders: a preliminary study. Except for the unstable glucolanadoxine, the known major components isolated from the leaves are glucogitoroside, glucoevatromonoside, digitalinum verum, gluco-digitoxigenine-glucomethyloside, glucodigifucoside, and glucogitofucoside. HIV-infected patients undergoing cesarean section are at increased risk for post-operative endometritis, but the severity of the infection is not different from that in HIV-negative patients.

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The available English language literature was reviewed for original research investigating in vitro, in vivo and clinical applications of radiolabeled MIBG for neuroblastoma. All these processes, if they result in bilateral restriction of airflow to the olfactory neuroepithelium, presumably alter the ability to smell. Doses were increased until the fasting blood glucose concentrations became less than 6 mmol/L (108 mg/dl), at which time the patients were admitted for a 24-h study period. It can be used to analyze the change of the aerodynamic in nasal cavity caused by the abnormal anatomy of the nose. Self-injurious behaviour (SIB) is a debilitating behaviour disorder that can have life-threatening consequences.

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The synthesis, and spectroscopic and electrochemical properties of hydrogenated tetraazaporphyrins (TAPs), namely tetraazachlorins (TACs), tetraazabacteriochlorins (TABCs) and tetraazaisobacteriochlorins (TAiBCs), have been reviewed. Confocal microscopy was done to determine nuclear translocation of AR. An intravenous infusion method is described for rapidly producing physical dependence in rats. We demonstrated that G alpha13 forms a complex with ASK1 in an activation-independent manner.

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These results were compared with those obtained through a standard approach and with an approach based on information content similarity. Standard Quad helix can be used to correct unilateral and bilateral dento alveolar posterior cross bite till first permanent molar. Potential benefit of maintenance trastuzumab and anastrozole therapy in male advanced breast cancer. This study analyzes ten cases of malignancy in a cohort of 183 renal transplant recipients, examining surgical management, postoperative immunosuppressive therapy, and long-term outcome. In addition, a decrease in the VEGF-A mRNA expression was found in the transitional areas between carcinomatous and sarcomatous elements in most carcinosarcomas evaluated.

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Stability of carotid artery under steady-state and pulsatile blood flow: a fluid-structure interaction study. These data are consistent with the hypothesis formulated from studies of non-human primates that dihydrexidine and other D1 agonists may be able to modulate prefrontal dopaminergic function.

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Mature retroviral CA proteins consist of two independently folded structural domains: N-terminal domain (NTD) and C-terminal dimerization domain (CTD), separated by a flexible linker. We have also produced chimeric mice carrying mardel(10) or NC-MiC1. IL2-caspase3 chimeric protein controls lymphocyte reactivity by targeted apoptosis, leading to amelioration of experimental autoimmune encephalomyelitis.

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Taurine (1 or 5 microg/ml) significantly attenuated the increases in the levels of LDH, ADMA, TNF-alpha and MDA, and the decrease in the level of NO and the activity of DDAH induced by ox-LDL in HUVECs. E3 ubiquitin protein ligase, E6-associated protein (E6-AP) regulates PI3K-Akt signaling and prostate cell growth. Moreover, the effect of the mutation on proteolytic processing and release of virus-like particles (VLPs) from human cells in culture was determined.

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We design an all-DNA system that behaves like vitrimers, innovative plastics with self-healing and stress-releasing properties. A thorough history and physical examination, tuberculin test, staining for acid-fast bacilli, radiologic examination, fine-needle aspiration and PCR will be instrumental in arriving at an early diagnosis early institution of treatment before a final diagnosis can be made by biopsy and culture. The same phenomena take place when the cells are bound to the glass by glutaraldehyde. Importins recognize their substrates in the cytoplasm and transport them through nuclear pores into the nucleus. These chemically patterned surfaces allowed the study of cells confined to particular regions of the substrate as a function of incubation time.

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Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors. This paper describes the preparation of cross-linked polynorbornene coated gold nanoparticles. Recombination detection algorithm in REDHORSE was able to detect conventional crossovers and double crossovers typically associated with gene conversions whilst filtering out artifacts that might have been introduced during sequencing or alignment. Improved estimation of human cortical activity and connectivity with the multimodal integration of neuroelectric and hemodynamic data. Substantial cancellation occurred also for locally extended patches of simulated activity, when the patches extended to opposite walls of sulci and gyri.

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Furthermore, these inhibitory synapses display an age-dependent form of long-lasting depression when activated at a low rate, suggesting that this process could support inhibitory synaptic refinement. Vascular regulation can be improved systemically with magnesium. A probable case of the homozygous condition of the aniridia gene.

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Finite element analysis of a knee joint replacement during a gait cycle. The obtained results may be of great importance for maximizing the imaging properties of OCT in tissue imaging. The clinical picture, clinical course and magnetic resonance imaging findings were characterstic of primary white matter disease, probably, vacuolated megalencephalic leukoencephalopathy with subcortical cysts (MLC). Our findings indicate that close attention should be paid to hospitalized patients with high CRP not only because of very substantial short-term risk, but also long-term excess risk, the basis for which needs to be determined. The results of this study support ALH as a safe and effective treatment option in this group of patients.

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An iterative case-study process of review, discussion, and re-review of documents to identify themes relevant to the design and conduct of ADVANTAGE. The present study demonstrated that the development of HCC was the most common cause of disease progression, and we also identified the risk factors associated with disease progression. Small and generally unreactive, organic azides are ideally suited for this task: they can be carried unnoticed through multiple biosynthetic steps only to be revealed, when desired, by action of a suitably derivatized visualization label. Successful transfection of sal-1 suggests that the L-form may be amenable to genetic modification with exogenous DNA.

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Study on the modified surface layers of the CIGS thin films by Raman spectra Veracious result is obtained, which shows the great potential of wavelet an lifting scheme in the application in speech processing strategy for cochlear implants based on characteristics of Chinese language. Lack of evidence to support the glyoxalase 1 gene (GLO1) as a risk gene of autism in Han Chinese patients from Taiwan.

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The recombinant protein (rSjEDF-I) shows certain immunogenicity, and is detected only in schistosomula and adult worms. Countermanding saccades with auditory stop signals: testing the race model. Can clinical data predict progression to dementia in amnestic mild cognitive impairment? Almost three years later, the patient showed right-sided hemiparesis that ultimately progressed to complete hemiplegia and advancing cognitive deterioration with a poor clinical outcome. The aim of this article is to present ranibizumab as a safe drug in treating wet AMD patients.

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A random sample of 2009 primary care physicians participated in the investigation. younger subjects and, thus, is a suitable first-line pharmacotherapy treatment for OAB in this population. Here we describe a xenograft approach to investigate how heterotypic tissue interactions control antler formation in deer.

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Detection of clonal IGH gene rearrangements: summary of molecular oncology surveys of the College of American Pathologists. Consequently, their projection when oriented towards the viewer is the same as when oriented away. In general, married persons had the lowest mortality, except for men older than 64 years where the lowest mortality was found in the never married category.

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Lipids and related parameters in Saudi type II diabetes mellitus patients. A Markov model based on the Intergroup Exemestane Study (IES) population compared switching to exemestane versus continued tamoxifen for 2.5 years of therapy and 5 years of postadjuvant therapy follow-up. Among themes of cost savings, workflow efficiency, and quality, the only benefits to be reliably documented were those regarding efficiency, including improved access to test results and other data from outside the practice and decreased staff time for handling referrals and claims processing. There is a broad consent between German forensic psychiatrists that the described changes in criminal law and the increasing application of preventive detention will intensify antiliberal tendencies not only within jurisdiction but also within forensic and general psychiatry.

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Several network modules of co-expressed genes correspond to interneuron development programs, in which the hub genes are known to be critical for interneuron specification. Previous studies show that natural killer cells have a pivotal role in the immune control of endometriosis. Other relevant tests included anti-nuclear antibody, human immunodeficiency virus, Venereal Diseases Research Laboratory, platelet count, echocardiography and carotid Doppler. We take an alternative approach, meeting the cardinality constraint first and matching values next. It is speculated that rifampicin may lead to an alteration in the enzyme system involved in the synthesis of inhibitory substances or, alternatively, to the formation or activation of enzyme systems involved in the sequestering of inhibitory substances.

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Interventions for preventing and treating hyperthyroidism in pregnancy. The purpose of this study was to investigate the presence of oxidative DNA damage in the photoreceptors of the rd1 mouse, an animal model for retinitis pigmentosa, and to determine if antioxidants could delay the progress of photoreceptor cell death. We aimed to estimate the prevalence of self-reported STIs and delineate their determinants among male migrant factory workers in Faridabad, Haryana.

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Chemical and mineralogical characterization of blast-furnace sludge from an abandoned landfill. All nodules showed marked or mild iron deposits in hepatocytes and/or kupffer cells, and a diffuse capillarization of the sinusoids. Liver metastasis predicts poorer prognosis in stage IV lung adenocarcinoma patients receiving first-line gefitinib.

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Recent discussion regarding whether the noise that limits 2AFC discrimination performance is fixed or variable has focused either on describing experimental methods that presumably dissociate the effects of response mean and variance or on reanalyzing a published data set with the aim of determining how to solve the question through goodness-of-fit statistics. It is worthwhile to monitor the risk for development of cardiovascular diseases in this group of children. There was a decline in C3 and C4 levels in both groups of patients.

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Acute effects of selective fetoscopic laser photocoagulation on recipient cardiac function in twin-twin transfusion syndrome. A review of controlled studies suggest that buprenorphine/naloxone is not likely to be any more or less effective than methadone, but since it will be less expensive in the long run, it may be more cost-effective than methadone when provided to comparable groups of patients. Both sisters were found to be heterozygous for the R482Q mutation in the lamin A/C gene (LMNA) gene, establishing the definitive diagnosis as Dunnigan-type familial partial lipodystrophy complicated by severe insulin resistance and secondary PCOS. This is important because the loss in elasticity of epithelial tissues with aging contributes to many human diseases.

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Interbeat interval modulation in the sinoatrial node as a result of membrane current stochasticity-a theoretical and numerical study. High levels of proteolysis and low levels of water-insoluble calcium were associated with decreased post-melt chewiness and whiteness of low fat Mozzarella cheese. Their combined deficits, however, synergized to cause postnatal death by severely impairing bone formation. Classical type III RH affords the complete resection of all paracervical lymphatic pathways potentially draining the cervix, however this procedure implies a high risk of lesions of the autonomous nerves of pelvic organs. This is the first report of the use of a slightly modified dose schedule for PLD at a dose of 40 mg/m2 every 3 weeks, which is active in platinum-refractory EOC with manageable toxicities.

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Intravenous administration of vitamin D provides advantages over oral administration, though no definite evidence could show which is better. Mechanisms underlying reduced apoptosis in neonatal neutrophils. We examined the influence of chronic adrenocorticotropic hormone (ACTH) treatment on the number of Ki-67-positive cells in the dentate gyrus of the hippocampus in rats. Interleukin-2 for the treatment of human immunodeficiency virus infection.

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If the conservative treatment is ineffective and there is a history of anterior spine surgery, the clinicians should consider the displacement of the plate or screws in differential diagnosis. Ultrasound-guided fine-needle cytology was performed in all cases and percutaneous core biopsy was considered necessary in three cases. Bone morphogenetic proteins (BMPs) are expressed during osteogenesis and their action is regulated by corresponding BMP inhibitors. We evaluated complementary and alternative medicine (CAM) use among a medically underserved, predominately Hispanic community at the University of California Irvine Family Health Center, a federally qualified health center. Among the group with positive results, 9 of 11 had rapid improvement of their gastrointestinal symptoms.

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During the last decade, research progress on cervical cancer has elucidated the role of human papilloma virus (HPV) in the pathogenesis of cervical cancer. This suture is partial, limited laterally by osseous trabeculae. To summarize validated risk stratification tools for predicting negative outcomes, with a specific focus on multimorbidity. Therefore, to investigate the biochemical effects of protein knockdown, it is necessary to purify the transfected cells. Self-organization of 2-acylaminopyridines in the solid state and in solution.

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Leukotrienes are thought to play a role in the pathogenesis of atopic eczema/dermatitis syndrome (AEDS). Reactive oxygen, nitrogen and chlorine species are created in inflammatory conditions, ischemia and tissues reperfusion. Physical fitness was evaluated by testing the performance on these trained components. The effect of expressed VEGF165 on VEC proliferation was detected by flow cytometry.

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The clinical utility, reliability and validity of the diagnosis remains to be established. Fluorescent probes for non-invasive bioenergetic studies of whole cyanobacterial cells. Development of a multiplex PCR-based rapid typing method for enterohemorrhagic Escherichia coli O157 strains. Tissue samples were dissected out from the upper and middle intestines and liver after development of nephrosis to measure the expression levels of mRNA and protein. The distribution and species specificity of human and mouse trophoblast-specific surface antigens detected by heterologous anti-mouse ectoplacental cone (anti-EPC) trophoblast and anti-human first-trimester trophoblast plasma membrane (anti-TrPM) antisera were assessed using several immunochemical and immunolabelling assays.

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We should be cautious of possible pyloric obstruction as the cause of prolonged pain after left hepatectomy. The possible reason that the expression of CK19 mRNA in the cancerous tissues was higher than that in para-cancerous tissues and normal oral mucosa was that the CK19 synthesis in cancerous tissues increased obviously. Impact of iodinated contrast difnal 100mg to ml injections on percent diameter coronary arterial stenosis and implications for trials of intracoronary pharmacotherapies in patients with ST-elevation myocardial infarction. Inhibitory effects of Saururus chinensis and its components on stomach cancer cells. The parameters of acidity, concentration and debit of pepsin, partial secretion, alkaline-acidic and acidic-peptic coefficients were determined in patients with the ulcerous disease.

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Tuberculosis (TB) is the major opportunistic infection of HIV-infected patients in developing countries and is associated with activation of the immune system and increased HIV-1 expression. Epidemiologic observations clearly demonstrate that African-Americans present with an earlier onset of hypertension, and experience higher rates of morbidity and mortality associated with elevated levels of blood pressure. Newly developed approaches continue to exploit their excellent catalytic potential to degrade hydrogen peroxide while (per)oxidase activity of catalases is opening a new range of possibilities as well. We discuss how the corresponding mutations might drive the pantoprazole sodium delayed release tablets 40 mg adaptation and onward transmission of the newly formed reassortant viruses.

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The safety of conservative surgery and the benefit of additional interventions after surgery for borderline ovarian tumours are unknown. Ventral sacral-rectopexy with mesh corrects rectal prolapse and minimises rectal dissection. Among 48 clones, one clone was chosen for its little constitutive enhanced green fluorescent protein (EGFP) expression and high spiroctan 75 mg forum level of EGFP expression after activation by BFV infection. When mixed prime:boost regimens using LAIV and IIV were studied, we observed a boosting effect in mice after priming with LAIV that was not seen when IIV was used as the prime.

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Understanding processes regulating prostate cancer cell survival is critical to management of advanced disease. Effects of eutrophic seawater and temperature on the physiology and morphology of Hypnea musciformis J. We also detected the direct interaction of the extremely acidic C-terminal polypeptide of tubulin with SPAS-1. The precise regulation of DSCR gene expression is antibiotico levofloxacin 500 mg crucial to maintain the brain homeostasis, especially in those areas with high levels of gene expression associated with a remarkable process of learning and cognition.

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Although initially described as a transfusion related viral infection, the disease can occur in sporadic, endemic, and epidemic settings. Recent findings on its roles in obesity, diabetes, and atherosclerosis, including GPER-dependent regulation of lipid metabolism and inflammation, are presented. There are some common features in terms of the etiology, diagnosis and treatment of these two tumors which are discussed. The number of morphotypes and population levels of total bacteria, vibrio antibiotic bactrim uti and Bacteroides tended to be higher in summer and autumn in the reservoir, and not different in the river. To examine the role of phonotactic probabilities at the onset of language development, in a new language (Dutch), while controlling for word position.

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Two recently developed video-optical intubation devices, the video-optical intubation stylet (VOIS) and the angled video intubation laryngoscope (AVIL) were compared for intubation times and success rate in a simulated difficult tracheal intubation setting. Using information from published data, clinical flutamide ointment management pathways were constructed and clinical outcomes identified. Ang II provokes rapid neutrophil recruitment, mediated through the release of CXC chemokines such as CINC/KC and MIP-2 in rats and IL-8 in humans, and may contribute to the infiltration of neutrophils observed in acute myocardial infarction. Yet, in all sympatric locations, the differences between the two species in these characters were highly significant. To correlate non-invasively detectable indicators of coronary atherosclerosis, or Coronary Artery Disease (i.e., classical risk factors, hs-CRP test results, carotid intima-media thickness, endothelial function, ankle-brachial index and calcium score by computed tomography) with the extent of coronary disease assessed by the Friesinger index from conventional coronary angiography.

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