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Topictal (Topiramate)
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Topiramate

Topictal can be in combination with other drugs to treat partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome (a severe form of childhood epilepsy). Topictal has both its approved and off-label uses. In the United States, the drug is officially approved by the U.S. Food and Drug Administration (FDA)

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Topictal is used alone or with other medications to treat certain types of seizures including primary generalized tonic-clonic seizures (formerly known as a grand mal seizure; seizure that involves the entire body) and partial onset seizures (seizures that involve only one part of the brain). Topictal is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topictal is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur. Topictal is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.

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Recovery in innate effector cells was defined by using an established murine model of autologous bone marrow transplantation. In a retrospective study of patients treated in the University of Washington Affiliated Hospitals, hypopharyngeal stenosis was more frequent after laryngectomy with partial pharyngectomy than after laryngectomy alone and occurred more commonly in lesions of the pyriform fossa than in glottic tumors. Spectral amplitude coding OCDMA using and subtraction technique.

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Measure the self-reported prevalence of HIV, history of HIV testing and associated risk factors among injecting drug users (IDUs) attending the Sydney Medically Supervised Injecting Centre (MSIC). miR-503 was found up-regulated in EC tissues compared to adjacent normal tissues. The delivery of peptide drugs via the buccal mucosa is more convenient and safe approach than most other delivery methods. This combined procedure can be recommended for stabilization of isolated chronic dorsolateral calcaneocuboid joint instability.

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However, concern for radiation exposure, which is substantial with computerized tomography (CT), has also grown. Porphyromonas gingivalis and Peptostreptococcus micros were found more frequently in AP and RPP patients, while Actinobacillus actinomycetemcomitans and Eikenella corrodens were associated with AP, LJP and RPP patients. In this pilot study, the observation that PDOF is not characterized by an increased aneuploidy rate (controlled for age) suggests that PDOF does not represent a simple shift of the physiologically declining ovarian function curve toward younger age.

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Calcium signals induce liver stem cells to acquire a cardiac phenotype. The synteny with experimental loci may eventually facilitate their identification. Ten patients were followed prospectively and received sirolimus, to achieve a target blood level of 10 to 15 ng/ml, induction therapy with one dose of daclizumab, low-dose steroids and mycophenolate mofetil.

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The Hospital Anxiety and Depression Scale (HADS) is widely used in the assessment of anxiety and depression, but there are scarce data about its psychometric properties in caregivers of older relatives. These results were not obtained on the basis of expression change alone.

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Pulmonary hypertension is a common cause of functional tricuspid regurgitation (TR), but other factors play a role in determining TR severity. Although the mass shared similarities with retrorectal cystic hamartoma (tailgut cyst) and juvenile polyps, described in human medicine, location and histologic findings were not entirely consistent with either condition. The objective of this study was to evaluate the long-term surgical outcome and recurrence rate of this technique in children. Similarly, these theories often include the consequences of behavior-influencing variables of interest (e.g., short-term reductions in negative affect). JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis.

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Research studies have been abstracted to support action items in a Blueprint for Transforming the Lives of Children, through the childbearing and early child rearing phases of family life. Widespread underrecognition and undertreatment of anxiety and mood disorders: results from 3 European studies. Differential matrix rigidity response in breast cancer cell lines correlates with the tissue tropism. Total knee arthroplasty is a common and immensely successful surgical procedure that reliably relieves pain and improves function. In the present study, we investigated the expression and prognostic value of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer as well as their relation to transcription factor activator protein (AP)-2 and HER2 oncogene.

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Salisphere cells were tested using 3D matrix culturing for their in vitro stem cell characteristics such as the potential to differentiate into tissue specific cell types. Here, we investigated the distribution of NO-sensitive guanylyl cyclase (NO-GC) in the spinal cord and in dorsal root ganglia, and we characterized the nociceptive behavior of mice deficient in NO-GC (GC-KO mice). Identification of a VWF peptide antagonist that blocks platelet adhesion under high shear conditions by selectively inhibiting the VWF-collagen interaction. Chronic infection should be considered when intrapelvic prosthetic migration occurs after total hip arthroplasty. Data were from three waves of the Korean National Oral Health Surveys between 2003 and 2010, including a total of 23 059 children (11 889 boys and 11 170 girls) aged 8, 10, and 12 years.

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The present study demonstrated the distinctive expression of genes and proteins of the extracellular matrix molecules between cellular and acellular cementum. Development of a portable system for checking radioactive sources using long wave radio frequency identification. We showed that GM-CSF and IL-2, when co-administered locally in an emulsion with peptide, exert a synergistic effect in enhancing the immune response to the antigen. In some mussels, a high content of lipofuscin was observed in the lysosomes of the digestive cells. The purpose of this study was to evaluate whether kinematic multiphase and multislice MR imaging could reveal pelvic adhesions.

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Chronic obstructive pulmonary disease as a risk factor for coronary heart disease Thermal parametric imaging in the evaluation of skin burn depth.

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Glyceryl trinitrate and SIN-1A were more effective on the tracheal musculature than on the tracheal vasculature whereas isoprenaline was equally effective on both. Evaluation of a 6-month multi-disciplinary healthy weight management program targeting urban, overweight adolescents: effects on physical fitness, physical activity, and blood lipid profiles. Clinical measures of disease activity were not significantly correlated with circulating inflammatory markers.

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The experimental results are consistent with the simulation fairly well. Problems arising from the use of the HLA system in paternity testing. Staging and diagnosis of non-small cell lung cancer: invasive modalities. For such a program to be effectively applied, each member of the team should constantly monitor the parenteral diet, and there should be a frequent exchange of information and experiences.

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In all cases where intra-operative signals could be measured, near-nerve signals were also detected. Metabolic syndrome in patients with hypertension attending a family practice clinic in Jordan. The increase in GABA content could arise from several possible causes which are examined in this study using rat cerebral cortex slices as a model.

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In this review, we briefly describe miRNA biogenesis and discuss how miRNAs can act as oncogenes and tumor suppressors. The expression of a mutated form of Ras in A549 epithelial cells blocked the induction of IL-8 promoter activity, and MEK inhibitor blocked induction of IL-8 mRNA.

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We observed that the expressions of ADAM12 and activin A are modulated during osteoclast formation, whereas the FLRG expression seemed to remain quite constant. Cardiovascular safety of drugs not intended for cardiovascular use: need for a new conceptual basis for assessment and approval.

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There has been a concomitant increase in consumption of high-fat and high-sugar foods, and consumption of these foods is higher among boys and children from lower socio-economic groups. Incretin-based drugs and risk of acute pancreatitis: A nested-case control study within a healthcare database. All the extracts were evaluated for hepatoprotective activity on limited test models as hexobarbitone sleep time, zoxazolamine paralysis time and marker biochemical parameters. Betaine may thus be an important one-carbon source, particularly in MTHFR 677 TT subjects with inadequate B-vitamin status. The polyketide synthase gene cluster of similar organization has not been reported yet.

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There is a need for more evidence to confirm these findings, also in other working populations. Responses to bleaching herbicides by leaf chloroplasts of maize plants grown at different temperatures. We used the crystallographic coordinates of the DNA binding domain of ERalpha complexed to a consensus ERE as a starting point to simulate several complexes in which some nucleotides in the ERE sequence were mutated.

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However, both of the patients improved following resection of the occluded segments and lumbar sympathectomy. The results are discussed in connection with the problem of the improvement of vaccine strains against the threatening H5N1 pandemic. Off-label prescribing was found in the majority of children receiving rehabilitative services, a rate as high or higher than that reported in pediatric acute care or clinic settings. These effects are in agreement with others obtained by intracerebroventricular injection of epinephrine, suggesting that these neuropeptides might be released on CG after this injection and produce increased progesterone in blood. A number of modifiable risk factors have been identified as major contributors of CVD and should be a focus of primary, secondary, and tertiary prevention.

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Design of an amperometric biosensor using polypyrrole-microgel composites containing glucose oxidase. We have also shown that lowering the pH from 8.0 to 4.0 results in a similar (approximately 0.4 eV) decrease in reorganization energy for both blue (type 1) and purple (CuA) azurins, even though the reorganization energies of the two different copper centers are different at a given pH. The degrees of such changes are closely related with the degree of insulin resistance.

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Therefore, they are good candidate for pharmaceutical treatment of osteoporosis to prevent subsequent fractures. Management of acute bronchiolitis: can evidence based guidelines alter clinical practice? Suppressive effects of hyaluronan on MMP-1 daktagold information management and RANTES production from chondrocytes.

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Whereas adult sex differences in brain morphology and behavior result from developmental exposure to steroid hormones, the mechanism by which steroids differentiate the brain is unknown. Statistical comparative analysis of body composition techniques. This article presents the recruitment and retention challenges experienced in two clinical trials: one involving participants experiencing a first episode of depression and one involving participants experiencing a first episode psychosis. A reduction oxicodal y trileptal withdrawal symptoms of the external jaw adductor (A1) and a changed morphology of the intramandibular musculature were found in many Beloniformes. Indeed, in the literature, methods for these three problems were generally proposed separately given that statistical modeling for them are very different.

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Increased understanding of how these agents affect cellular aspects of growth and development of skeletal muscle and adipose tissue will allow cattle feeders, consultants, and researchers to instigate intervention strategies to ameliorate the reduced marbling scores. Trisomy dapoxetine online australian 8 is one of the most frequent numerical chromosomal abnormalities observed in hematological malignancies, whereas tetrasomy 8 is a clonal aberration seen mainly in myeloid disorders such as acute myelod leukemia (AML) and myelodysplastic syndromes.